Post-exposure prophylaxis during pandemic outbreaks

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Post-exposure prophylaxis during pandemic outbreaks

BACKGROUND With the rise of the second pandemic wave of the novel influenza A (H1N1) virus in the current season in the Northern Hemisphere, pandemic plans are being carefully re-evaluated, particularly for the strategic use of antiviral drugs. The recent emergence of oseltamivir-resistant in treated H1N1 patients has raised concerns about the prudent use of neuraminidase inhibitors for both tr...

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Supplementary Information: Post-exposure prophylaxis during pandemic outbreaks

1Institute for Biodiagnostics, National Research Council Canada, Winnipeg, Manitoba, Canada, 2Department of Mathematics and Statistics, The University of Winnipeg, Winnipeg, Manitoba, Canada 3Analysis and Stochastics Research Group, Hungarian Academy of Sciences, Bolyai Institute, University of Szeged, Szeged, Hungary 4Dalla Lana School of Public Health, University of Toronto and Ontario Agency...

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Factors associated with delay in post-exposure prophylaxis in

  Background :Although the incidence of animal bite is increasing in Iran, there is no sufficient knowledge about delayed Post-Exposure Prophylaxis (PEP). Hence, the aim of this study was to evaluate delayed PEP and its associated factors in bitten people.   Methods : This cross-sectional study was conducted in Tuyserkan district of Hamadan Province (West of Iran) from February 2011 to February...

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Evaluation of vaccination strategies during pandemic outbreaks.

During pandemic influenza, several factors could significantly impact the outcome of vaccination campaigns, including the delay in pandemic vaccine availability, inadequate protective efficacy, and insufficient number of vaccines to cover the entire population. Here, we incorporate these factors into a vaccination model to investigate and compare the effectiveness of the single-dose and two-dos...

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Varicella vaccine in post-exposure prophylaxis.

Evidence concerning the effectiveness of Oka-based varicella vaccines when administered following exposure to varicella zoster virus in domestic and hospital settings is reviewed. The evidence appears to support post-exposure use of Oka-derived varicella vaccines in children within 3 days of rash onset in the index case. Despite vaccination, a small proportion will develop mild, but infectious,...

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ژورنال

عنوان ژورنال: BMC Medicine

سال: 2009

ISSN: 1741-7015

DOI: 10.1186/1741-7015-7-73